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Genetic Engineering

How can genetic engineering enable microscopic organisms to tackle huge ecological challenges?

DNA double helix close up

Creative Artifact

Students become synthetic biologists as they design a custom plasmid to transform everyday bacteria into living biosensors that detect local environmental pollutants. They’ll showcase their innovation on a collaborative website modeled after the iGEM competition, blending science, storytelling, and design.

Written Commentary

The Google Site includes two written explanations. Students select a local pollutant, describing its sources and the communities it threatens and explain why it is a worthy target of an engineering project. Additionally, students describe their plasmid and explain how it will work using pictures and words.

Exhibition

Based on their work during the unit, students script a 90-second elevator pitch for community members in which they describe their genetically engineered organism and how it would work at a cellular and molecular level. Students will also propose the potential applications and benefits of this biosensor to their specific local community, emphasizing its significance in environmental remediation and human health.

Implementation Notes

Credit Eligibility

  • microscope icon

    Science

Prerequisites Needed

N/A

Modular Suggestions

An application-based unit within a course tied to Biology or Life Science. (Compatible with the OpenSciEd Biology Sequence).

 

TLE-Based Semester/Full-Year Course Suggestions

Biology:
Plant Power,
Genetic Engineering

Standards Addressed

  • HS-LS2-7: Design, evaluate, and refine a solution for reducing the impacts of human activities on the environment and biodiversity.* 
  • HS-LS1-1: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
  • HS-LS3-1:  Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring.
  • HS-LS3-2: Make and defend a claim based on evidence that inheritable genetic variations may result from (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.
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